Papers
1.Shuguang Bao, He Bu, Shan Dong, Yajie Wang, Rui Liu, Hui Wang, Wenlong Ma, Zhuo Li, Na Shen, Tao Lin, Juan Chen, Qi Wan*. Identification of NMT1/MA/VPS15 signal pathway as potential therapeutic target in rat cerebral ischemia injury. Experimental Neurology. 2025 April. doi.org/10.1016/j.expneurol.2025.115252
2.Wenjia Du, Huanhuan Chen, Ilona Gróf, Lucien Lemaitre, Alexandra Bocsik, Adrian Perdyan, Jakub Mieczkowski, Mária A. Deli, Tibor Hortobágyi, Qi Wan & Oleg O. Glebov. Antidepressant-induced membrane trafficking regulates blood-brain barrier permeability. Molecular Psychiatry. 2024; DOI:10.1038/s40380-024-02626-1
3.Hui Wang, Wenlong Ma, Wenjie Hu, Xiaohua Li, Na Shen, Zhuo Li, Xiangyi Kong, Tao Lin, Jingchen Gao, Ting Zhu, Fengyuan Che, Juan Chen, Qi Wan*. Cathodal Bilateral Transcranial Direct-Current Stimulation Regulates Selenium to Confer Neuroprotection after Rat Cerebral Ischemia-Reperfusion Injury. The Journal of Physiology (London). 2024; DOI:10.1113/JP285806
4.Yu Cui, Zhaolong Zhang, Mengfei Lv, Zhongying Duan, Wenhao Liu, Jingchen Gao, Rui Xu, Qi Wan*. Chromatin target of protein arginine methyltransferases alleviates cerebral ischemia/reperfusion-induced injury by regulating RNA alternative splicing. iScience. 2023; doi.org/10.1016/
5.Xin Zhou, Rui Zhao, Mengfei Lv, Xiangyu Xu, Wenhao Liu, Xiaohua Li, Yunyi Gao, Zhiyuan Zhao, Zhaolong Zhang, Yuxuan Li , Rui Xu, Wan Q, Yu Cui. ACSL4 Promotes Microglia-Mediated Neuroinflammation by Regulating Lipid Metabolism and VGLL4 expression. Brain Behav Immun. 2023 Feb 13;S0889-1591(23)00037-5. doi: 10.1016/j.bbi.2023.02.012.
6.Cheng J, Fan YQ, Jiang HX, Chen SF, Chen J, Liao XY, Zou YY, Lan HY, Cui Y, Chen ZB, Chen QX，Wan Q*. Transcranial direct-current stimulation protects against cerebral ischemia- reperfusion injury through regulating Cezanne-dependent signaling. Experimental Neurology. July 27, 2021, doi.org/10.1016/j.expneurol.2021.113818.
7.Liu R, Liao XY, Pan MX, Tang JC, Chen SF, Zhang Y, Lu PX, Lu LJ, Zou YY, Qin XP, Bu LH, Wan Q*. Glycine Exhibits Neuroprotective Effects in Ischemic Stroke in Rats through the Inhibition of M1 Microglial Polarization via the NF-κB p65/Hif-1α Signaling Pathway. J Immunol. 2019;202(6):1704-1714
8.Zhang ZF, Chen J, Han X, Zhang Y, Liao HB, Lei RX, Zhuang Y, Wang ZF, Li Z, Chen JC, Liao WJ, Zhou HB, Liu F, Wan Q*. Bisperoxovandium (pyridin-2-squaramide) Targets Both PTEN and Erk1/2 to Confer Neuroprotection. British Journal of Pharmacology 2017; 174(8):641–656. doi: 10.1111/bph.13727
9.Chen J, Zhuang Y, Zhang ZF, Wang S, Jin P, He C, Hu PC, Wang ZF, Li ZQ, Xia GM, Li G, Wang Y, Wan Q*. Glycine confers neuroprotection through microRNA-301a/PTEN signaling. Molecular Brain. 2016; 26; 9(1):59.
10.Hu R, Duan B, Wang D, Yu Y, Li W, Luo H, Lu P, Lin J, Zhu G, Wan Q and Feng H: Role of acid-sensing ion channel 1a in the secondary damage of traumatic spinal cord injury. Annals of Surgery 2011;254:1–10
11.Chang N, Li L, Hu R, Shan Y, Liu B, Li L, Wang H, Feng H, Wang D, Cheung CC, Liao M and Wan Q*: Differential regulation of NMDA receptor function by DJ-1 and PINK1. Aging Cell. 2010; 9:837–850
12.Cheung CC, Yang C, Berger T, Zaugg K, Reilly P, Elia AJ, Wakeham A, You-Ten A, Chang N, Li LJ, Wan Q, and Mak TW: Identification of BERP (brain-expressed Ring finger protein) as a p53 target gene that modulates seizure susceptibility through interacting with GABA-A receptors. Proc Natl Acad Sci USA. 2010; 107(26):11883-8
13.Liu B, Li L, Zhang Q, Chang N, Wang D, Shan Y, Li L, Wang H, Feng H, Zhang L, Brann DW and Wan Q*: Preservation of GABAA receptor function by PTEN inhibition protects against neuronal death in ischemic stroke. Stroke 2010; 41(5):1018-26
14.Li L, El-Hayek YH, Liu BS, Chen Y, Gomez E, Wu XH, Ning K, Li LJ, Chang C, Zhang L, Wang ZG, Hu X, Wan Q*: Direct-current Electrical Field Guides Neural Stem/progenitor Cell Migration. Stem Cells 2008; 26(7): 1610-1836
15.Chang N, El-Hayek YH, Gomez E and Wan Q*: Phosphatase PTEN in neuronal injury and brain disorders. Trends in Neurosciences 2007; 30(11): 581-586
16.Ning K, Li L, Liao M, Liu B, Mielke JG, Chen Y, Duan Y, El-Hayek YH, Wan Q*: Circadian regulation of GABA(A) receptor function by CKIepsilon-CKIdelta in the rat suprachiasmatic nuclei. Nature Neuroscience. 2004; 7(5):489-490
17.Ning K, Pei L, Liao M, Liu B, Zhang Y, Jiang W, Mielke JG, Li L, Chen Y, El- Hayek YH, Fehlings MG, Zhang X, Liu F, Eubanks J, Wan Q*: Dual neuroprotective signaling mediated by downregulating two distinct phosphatase activities of PTEN. Journal of Neuroscience. 2004; 24(16):4052-60
18.Wan Q, Man HY, Liu F, Braunton J, Niznik HB, Pang SF, Brown GM, Wang YT: Differential modulation of GABAA receptor function by MEL1a and MEL1b receptors. Nature Neuroscience. 1999; 2(5): 401-403
19.Wan Q, Xiong ZG, Man HY, Ackerley CA, Braunton J, Lu WY, Becker LE, MacDonald JF, Wang YT: Recruitment of functional GABAA receptors to postsynaptic domains by insulin. Nature. 1997; 388:686-690